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The Arrow #242
Hello everyone.
I’m here to tell you that the shittification of everything has consumed the airlines completely. MD, our son, and I had a meeting in Ashland, Oregon on Tuesday morning this week. All it required to get there was two short flights, each lasting 45-55 minutes wheels up to wheels down and a short drive from Medford, OR to Ashland.
All flights both coming and going were screwed up. Our plan was to fly out of Santa Barbara through San Francisco and get into Medford/Ashland at about 5:30. We would check into the hotel, have a nice dinner, hit the rack, then get up and go to the 9 AM meeting.
After multiple delays, flight cancelations, etc, we ended up getting in after midnight. The two ‘short’ flights back were the same. Long delay at the Medford airport, so we were likely to miss our connecting flight to Santa Barbara. But in keeping with uniform airline incompetence, that flight was also delayed, so we figured we might have a chance. We sprinted through two concourses at the San Francisco airport only to discover the gate had been closed moments before we got there. Ugh!
This has happened to me a few times when racing for a tight connection after a delayed flight. I’ve always been told it is the pilot’s decision when to close the gate, and when it is closed, it is closed. This time, however, the pilot reopened the gate and let us on along with a handful of others who came before and after us. They had already rebooked us, so we had no seats. They just told us to sit wherever we could find a seat. Which we did. So we got back to Santa Barbara about an hour after scheduled.
I am forever grateful to that United Airlines pilot and the flight and gate crew and thanked him/them effusively when we disembarked from the plane.
Four short flights ended up making for a stressful 24 hours, but at least we made our meeting.
Every time I write about airline nightmares, I always get a nasty comment or four from people saying don’t waste my time blathering about airline travel. We all know it’s awful.
But does it have to be? What is the problem? There have been multiple problems with the last 10-12 flights I’ve taken ranging from mechanical issues to crews not being available. There is something wrong with the system.
Others write that they love to read my rants about travel screwups. Wasn’t much of a rant here, but for those of you who love to read about the misfortunes of others, here is the worst airline screwup story I’ve heard in a long time. I’ve missed one European flight thanks to an airline error and had to spend the night in a hotel, but nothing of this magnitude.
Learn from this investor’s $100m mistake
In 2010, a Grammy-winning artist passed on investing $200K in an emerging real estate disruptor. That stake could be worth $100+ million today.
One year later, another real estate disruptor, Zillow, went public. This time, everyday investors had regrets, missing pre-IPO gains.
Now, a new real estate innovator, Pacaso – founded by a former Zillow exec – is disrupting a $1.3T market. And unlike the others, you can invest in Pacaso as a private company.
Pacaso’s co-ownership model has generated $1B+ in luxury home sales and service fees, earned $110M+ in gross profits to date, and received backing from the same VCs behind Uber, Venmo, and eBay. They even reserved the Nasdaq ticker PCSO.
Paid advertisement for Pacaso’s Regulation A offering. Read the offering circular at invest.pacaso.com. Reserving a ticker symbol is not a guarantee that the company will go public. Listing on the NASDAQ is subject to approvals.
After writing last week about the weirdness of Boulder, I had great trepidation about opening my email the next morning. Sure enough, the first two were from people writing telling me to unsubscribe them. Pretty much everyone these days is sophisticated enough to know all you have to do to unsubscribe from an email is to scroll to the bottom and hit the unsubscribe button, and you’ll be unsubscribed. Those who want to send a message demand to be unsubscribed.
As I went through the poll responses, they were all uniformly in line with my position on Boulder’s weirdness.
Boulder advertises itself as being weird, so why would people mind being characterized as such? Boulder is a gorgeous place. I’ve always said Boulder is like a flawlessly beautiful woman that you’re just not in love with. I could never get with the Boulder groove the entire time we lived there.
We split our time back in those days pretty much between Boulder and Santa Fe, NM, which is another weird place. It formally advertises itself as the ‘City Different’. But the Santa Fe weirdness didn’t wear on me or MD. We loved it. I guess we’re just more Santa Fe weird than we are Boulder weird.
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What Are Shrinks All About?
When I started medical school it was with the intent of becoming a surgeon, a plastic surgeon, in fact. The first two years of medical school are basically classroom work. You get a little bit of patient contact, but it’s mainly just observing real doctors questioning patients. The rest is college-on-steroids lecture hall stuff.
The second two years are the clinical years during which you actually interact with patients. You go through multiple rotations of the major specialities : internal medicine, surgery, ob-gyn, pediatrics, and psychiatry. The senior year is pretty much devoted to electives in those subspecialties you might want to learn more about.
As I said, my intent starting medical school was some sort of surgical specialty. But I almost got hijacked by psychiatry. I had no idea I would enjoy it as much as I did. In fact, I figured I would hate it, because most of the people I knew who had taken it before I did hated it. But I loved every minute of it. In fact, I actually contemplated switching from surgery since I enjoyed it so much.
I had an excellent mentor, which helped a lot. And I learned how psychiatry really functioned. It wasn’t just talking crazy people down off the roof (though there was some of that), but rather mainly it was about helping more or less normal people solve problems they were having difficulty solving on their own. Usually, interpersonal relationships.
When seeing a new patient for the first time, a psychiatrist seeks a diagnosis. There is an entire manual of psychiatric diseases called the DSM. Once a patient is diagnosed, then there is a treatment protocol.
Most of the people seen by your average psychiatrist fall into the category of “adjustment” disorders. Most are probably adjustment disorders to adult life. You can read about them here.
What brought this all to my mind was a commentary piece in yesterday’s Wall Street Journal about the Democratic contender for New York City mayor Zohran Mamdani under the title below. I encourage you to read it.

Reading the article whisked me back to the many sessions I had with my psychiatry mentor and the many, many patients, friends, and family I have observed going to therapists.
The author, himself a psychotherapist, writes:
A patient recently came to my New York therapy practice, shaken after witnessing a violent assault outside her apartment. “This is why we need Mamdani,” she said, referring to Zohran Mamdani, the socialist mayoral candidate who wants to replace police with social workers—a policy that feels good but actually fuels the urban decline my client witnessed. After more than two decades as a psychotherapist, I understand the reflex to trust a comforting illusion, in both therapy and politics.
In therapy, false relief traps patients in their problems. In politics, it traps cities in decline. Our cities are being run like bad therapy sessions—all processing, no progress.
Therapy works when it builds resilience, agency and accountability. Yet modern therapy too often prizes validating patients’ feelings over pushing them to grow. When that victim mindset drives policy, cities treat solvable problems as existential crises and avoid the hard work of fixing them. Just as many therapists turn patients’ everyday stress and conflict into “trauma,” modern politicians frame fixable issues like crime as problems too large to solve. [My bold]
In my view, there is a huge difference between a good therapist and a bad one. Good therapists bring about healing, and as the article says, it “builds resilience, agency and accountability.” A poor therapist promotes a downward spiral into victimhood.
Here is the difference.
Most issues bringing people to therapists are interpersonal issues. People can’t get along. Finally, one party decides to go to therapy to figure out a way to get through what seems to be an unsolvable problem. But as we all know, in most interpersonal problems, there is blame on both sides.
If the patient ends up with a good therapist, here is what happens. The therapist listens to the tale of woe, asking questions, and drawing out the patient with the goal of establishing rapport and trust. Once this is done—and it may take a few sessions—the therapist begins to confront the patient. This is impossible to do without first establishing the trust and rapport. When the therapist feels the patient is ready, the confrontation begins.
As I wrote about, in most interpersonal problems, there is blame on both sides. The therapist begins gently confronting the patient about his/her own role in the problem. It takes a skilled therapist to know when to initiate the confrontation and how hard to push it, which is all a function of how much trust the patient has with the therapist. It can be a tightrope to walk. It’s not necessarily a pleasant situation for either patient or therapist.
Over time, the patient comes to realize there is blame on both sides. Then work begins on how to solve the issue, knowing the patient is part of the issue. That’s when the healing, resiliency and agency comes about and the patient generally has a good outcome.
The bad therapist—in my view, at least—starts out the same and works to develop rapport. But instead of confronting the patient, the bad therapist tells the patient he is right. It’s all the other person’s fault. The patient is the victim, the other person involved is the perpetrator, and the therapist doesn’t solve anything. But it does make the patient feel good. He/she was right. He/she has been done badly. He/she devolves more into victimhood, but it feels good because it isn’t his/her fault. It’s all the other person(s).
I’ve seen people go to therapist like this forever. And they never improve, but they enjoy being told they are right, they are victims. The therapist makes a lot of money, the patient is happy to pay it to have a place to vent and have his/her victimhood confirmed.
The good confrontational therapist don’t always succeed. There are people out there—I know one, now deceased—who went to therapists all the time to have her victimhood confirmed. If she would have stumbled onto a good therapist, at the confrontational point, she would have been gone in a shot. She would have found another therapist in short order to make her feel good about her victimhood.
Maybe some of my readers out there who are therapists or psychiatrists can tell me what the ratios are between the two types of therapists. Are there more victimizers or more confronters? I would suspect the former.
People will pay to hear what they want to hear.
Which is what has happened to the New York Times and to a lesser extent to the Washington Post. Since we’ve gone into the digital age, newspapers have had to adapt. Not all that long ago, newspapers were supported almost totally by advertising. They could pretty much say what they wanted to say (as long as they didn’t piss off their advertisers) without concern. So they reported the news.
Now most of the big papers (probably the smaller ones too) have gone to the subscription model. The larger papers are making plenty of money, but if one of their writers writes something that their subscribers disagree with, they lose thousands of subscriptions. They’ve figured out what their readers want to read, and they provide it to them. For a price, of course. Just like the lousy therapists.
Dr. Kessler and the FDA GRAS Petition
Two or three weeks ago, I wrote about Dr.Kessler, who was appointed the FDA Commissioner by Bush I. At the time, Kessler was all in on the notion that fat, especially saturated fat, was the bête noire of the American diet. Of course, this was during the time MD and I were promoting a saturated-fat-rich, low-carb diet. Consequently, we ran up against Kessler’s (and the FDA’s) dietary recommendations all the time.
I thought when Bush lost to Bill Clinton in 1992 that would be the end of Kessler, and I was going to be happy to see the back of him. But, such was not the case. Clinton kept Kessler on as FDA commissioner for another term.
Sometime between then and now, Kessler must have gotten a brain transplant, because he has done a complete 180 on his nutritional outlook. He now believes refined carbohydrates are causing the obesity and diabetic epidemics were experiencing. He occasionally mentions saturated fats, but not often, and not with the disdain he now has for refined carbs.
He’s even gone so far as to write a book or two advocating low-carb diets. When I last wrote about Dr. Kessler, he was trying to get RFK, Jr. to encourage people to cut carbs as part of his MAHA agenda. To be honest, I almost couldn’t believe it.
Now he’s gone one better.
Dr. Kessler has filed a citizen’s petition to the FDA seeking revocation of GRAS status for processed, refined carbohydrates.
Here is the FDA’s definition of GRAS.
"GRAS" is an acronym for the phrase Generally Recognized As Safe. Under sections 201(s) and 409 of the Federal Food, Drug, and Cosmetic Act (the Act), any substance that is intentionally added to food is a food additive, that is subject to premarket review and approval by FDA, unless the substance is generally recognized, among qualified experts, as having been adequately shown to be safe under the conditions of its intended use, or unless the use of the substance is otherwise excepted from the definition of a food additive.
Under sections 201(s) and 409 of the Act, and FDA's implementing regulations in 21 CFR 170.3 and 21 CFR 170.30, the use of a food substance may be GRAS either through scientific procedures or, for a substance used in food before 1958, through experience based on common use in food Under 21 CFR 170.30(b), general recognition of safety through scientific procedures requires the same quantity and quality of scientific evidence as is required to obtain approval of the substance as a food additive…
Under 21 CFR 170.30(c) and 170.3(f), general recognition of safety through experience based on common use in foods requires a substantial history of consumption for food use by a significant number of consumers.
The petition Dr. Kessler filed was not a simple matter of a few pages. It is a 66 page, densely-worded document explaining precisely why processed, refined carbs should not be considered GRAS.
You can read the petition here on the FDA website. I pulled down the PDF version and put it in my Dropbox, which you can access here.
The petition is extremely thorough and is a devastating argument for why processed, refined carbs are problematic. I don’t really see the FDA ever considering carbs as not being GRAS, but, given Kessler’s standing with the government, this petition is more likely to bring it about than if I had written it.

Here is the summary.
In the last several decades, a significant body of scientific research has emerged demonstrating that refined carbohydrates used in industrial processing (herein after, processed refined carbohydrates) put people at risk for increased caloric intake, weight gain, fat accumulation in the liver, pancreas, skeletal muscle, and heart, and metabolic abnormalities. These lead to a cascade of chronic diseases, including heart and kidney diseases, type 2 diabetes, certain cancers, and possibly neurodegenerative disease. There is increasing concern about the ill effects of ultraprocessed foods, which are usually composed of 1) refined sweeteners, 2) refined flours and starches, 3) added fats and oils, and/or 4) salt. This petition focuses on the first two categories, both of which are processed refined carbohydrates. These processed refined carbohydrates are central to the widespread availability of ultraprocessed foods. [My bold]
Even though he throws in added fats and oils and salt, he is focused on the carbs.
“This petition focuses on the regulatory status of the following substances:
refined sweeteners, including corn syrup, corn solids, glucose syrups, dextrose, invert sugar, xylose, maltose, and high fructose corn syrups; and maltodextrin
refined flour and starches that are subjected to food extrusion technology, including wheat, corn, tapioca, oat and potato flour, and starches that are processed by extraction or similar technology, and
sucrose, refined flours, or starches that are used with emulsifiers (e.g. mono- and diglycerides of fatty acids, DATEM, sodium stearoyl lactylate, polysorbates); dough conditioners and strengtheners (e.g. azodicarbonamide, L-cysteine, calcium peroxide); humectants (e.g. propylene glycol); stabilizers and gums (e.g. carboxymethylcellulose, methylcellulose); or modified starches and fillers (e.g. regelatinized starch, modified food starch, dextrins).”
(Note: My platform, despite repeated requests on my part, doesn’t allow numbered lists inside quote boxes, so I’m using the workaround of just putting those in quotes, as I’ve done immediately above.)
Taking a look at the above list of ingredients in processed, refined foods, it’s easy to see that if we’re eating off the grocer’s shelves, we’re not really eating an ancestral diet. Hell, we not even eating the diet I ate when I was a kid in the 1950s.
This petition focuses on processed refined carbohydrates that are primary causal determinants of metabolic harm. These processed refined carbohydrates can themselves be “markers” of ultraprocessed foods (e.g. corn syrup, maltodextrin), or they can be used with other markers of ultraprocessed foods (e.g. emulsifiers, stabilizers, humectants).
Ultraprocessed foods are harmful. Processed refined carbohydrates are harmful. This petition focuses on processed refined carbohydrates in an environment of ultraprocessed food.
This petition does not cover flour, table sugar (sucrose), starch, salt, or corn syrup when used at home.
Processed refined carbohydrates are allowed on the market because almost 50 years ago they were found to be “generally recognized as safe” but, as this petition demonstrates, the science no longer supports that determination.
In light of the substantial concerns regarding the safety of processed refined carbohydrates, there is no longer a basis for finding that these products are “generally recognized as safe.” Past GRAS determinations are based on outdated data and fail to assess the long-term effects on insulin dynamics, blood lipid parameters, energy partitioning, inflammatory markers, brain reward signaling, or visceral adiposity. These past determinations do not reflect chronic exposure, synergistic effects with other additives, or lifetime health consequences. Today there is no expert consensus that refined carbohydrates in ultraprocessed foods are safe under present conditions of use, as is required to find that use of refined carbohydrates is GRAS.
The law places a continuing burden of proof on industry for the safety of GRAS substances. In other words, GRAS status of a specific use of a particular substance in food is time dependent and a product is not GRAS if there is no longer consensus that the specific use is safe.
Further, to revoke GRAS status, FDA does not have to prove that the processed refined carbohydrates used in industrial processing are unsafe, but that their safety has not been established.
Processed refined carbohydrates can no longer be considered GRAS as a matter of science and law, and thus must be removed from commerce unless marketed as permitted by a food additive regulation. [My bold]
As you can see from the bolded text above, this petition does not apply to flour, sugar, and the other condiments usually found in the home kitchen when used at home.
After laying out the ingredients he wants to be removed from GRAS, Dr. Kessler goes into why.
The American body is ill
Only 12.2% of Americans are metabolically healthy. Seventy-four percent are overweight or obese, and about 38% are insulin-resistant or prediabetic. About 1 in 3 adolescents 12 to 17 years old have prediabetes. Americans have a 23–25% lifetime risk of developing heart failure. They have a 40% lifetime chance of developing diabetes.
One in four will have a stroke. Some will develop kidney failure.
Visceral fat in the abdomen causes cardiac and kidney diseases, diabetes, certain forms of cancer, and dementia. Fifty to sixty percent of Americans will develop at least one of these conditions over their lifetime.
Cardiologists, nephrologists, and endocrinologists are recognizing that the epidemic of obesity causes these diseases.
According to the Centers for Disease Control (CDC), poor nutrition is at the center of this epidemic. This epidemic rivals tobacco in its damage to human health. [My bold]
Dr. Kessler goes into what he refers to as our being locked into the junk food cycle.
National and international authorities have observed that our current food system is locked in a “junk food cycle” that not only fails to deliver healthy food, but provides cheap industrial foods that are energy-dense, highly palatable, and have extended shelf life.

If you contemplate on it, you’ve got to kind of feel sorry for Big Food. Think about it. If you were running a Big Food company and needed to show growth to your stockholders, how do you do it?
There just aren’t that many ways to grow. You can grow a bit along with the population, which is ever expanding. But those are pretty small numbers. You can grow by acquiring another company. You can grow by taking business from competitors. And you can grow if somehow you get people to eat more, i.e., to increase their caloric intake.
As Kessler comments later on in the petition, “on average, Americans consume about 500 calories more daily than they did in 1970 (of which 210 are from carbohydrates, particularly flour, rice, and cereals).”
That’s close to a 20 percent increase in calories overall. Multiply that times all the people in the US, and it will account for a lot more food consumed now than in 1970.
You can’t blame Big Food for fighting for business. It’s difficult to grow if all you’re selling is meat, eggs, butter, cheese, and vegetables. You’ve pretty much got to have the snack foods that people eat mindlessly to keep up.
What I found most interesting about the petition was Kessler’s description of how food processing changed circa 1980.
The Industrial Transformation of Carbohydrates
In the 1980s, a major change occurred in the way that starch was processed from corn and chemically processed to produce sweeteners. Known as corn wet milling, it became the backbone in industrial food processing and allowed for the production of synthetic, highly palatable, energy-dense shelf foods. Estimates are that about 25% of grocery store items come from the products produced by corn milling.
In 1984, Professor Roy Whistler of Purdue University understood the major revolution that was occurring:
“Innovations have now brought the industry to a highly sophisticated level with up-to-date, state-of-the-art, continuous, economical processes for conversion of corn to starch and on to D-glucose of excellent quality. A significant further development was the introduction of advanced enzyme engineering to convert high-purity D-glucose to a mixture of D-glucose and D-fructose equivalent to invert sugar from sucrose, thereby opening to the corn industry the hitherto unavailable but enormous market in sweeteners. Solid entry into this market is provided by the stability of corn supply and the low cost of producing D-glucose–D-fructose syrup.” [My bold]
The products that are the focus of this petition are enzymatically, chemically, and physically made from cornstarch into readily absorbable glucose polymers or simple sugars.
These industrial starch-derived chemicals range in their level of sweetness. They were key to the emergence of ultraprocessed foods by increasing shelf stability, moisture and texture control, cost reductions, and customization of sweetness.
Unlike sucrose, these products do not crystallize but do retain moisture, allowing greater shelf life. They can act as humectants, emulsifiers, and bulking agents, resulting in softness, smoothness, and chewiness in a great variety of products.
Also unlike sucrose, these processed refined carbohydrates can be blended to achieve a range of sweetness in everything from bread, cereals, ketchup, sauces, yogurts, bars, shakes, and sodas.
Unlike traditional cornstarch that was used in home cooking, these processed refined carbohydrates are derived first by breaking down that starch and altering it chemically and then recombining it with fat, salt, and other food substances into ultraprocessed food-like structures that have none of the food matrix structure of traditional food and deliver increased carbohydrate loads. That food matrix structure had for thousands of years naturally controlled the release of sugars that result in insulin and glucose stimulation. Processing’s effects on the food matrix eliminates those natural “brakes” on insulin and glucose release.
What really kicked off the onslaught of processed foods was, believe it or not, corn.
How Corn Syrups Give Rise to Ultraprocessed Foods
Corn syrups were key to the increased availability of many ultraprocessed foods in part by improving the efficiency and functionality of food manufacturing. Unlike crystalline sucrose, which must be dissolved and carefully handled to prevent recrystallization, corn syrups are flowable liquids that can be directly metered into continuous production systems. Corn syrups are made by breaking down cornstarch through acid or enzymatic hydrolysis, producing a mixture of glucose and other saccharides. These mixtures resist crystallization, unlike sucrose, allowing the syrup to remain liquid and smooth, which makes it easier to handle in industrial food manufacturing without clogging equipment. This makes them especially compatible with large-scale processes like extrusion, spray drying, and aseptic packaging. Their resistance to crystallization made them ideal for soft drinks, baked goods, frozen desserts, and syrups—products that require stable textures and extended shelf lives under a range of storage conditions. Because these syrups are liquid at room temperature, they are particularly valuable for products like sweet baked goods because, along with the addition of oils (also liquid at room temperature), they can keep a product like a cake or muffin moist for 30 days or more in contrast to a homemade cake, which might be stale in a matter of days.
In addition to ease of handling, corn syrups offered chemical flexibility. Produced by hydrolyzing cornstarch, they can be tailored to have different levels of sweetness, viscosity, and browning potential depending on the degree of hydrolysis—measured as dextrose equivalent (DE). High-DE syrups like glucose syrup are highly sweet and hygroscopic, contributing to moisture retention and sweetness; low-DE syrups like maltodextrin provide bulk and body with little sweetness. This tunability allowed food manufacturers to precisely control product characteristics and tailor ingredients to specific formulations, something sucrose alone could not offer.
Perhaps most significantly, corn syrups enabled the creation of more energy-dense foods—that is, foods that deliver more calories per gram or per serving—by facilitating the formulation of high-solids products that retained desirable textures and stability. This was not simply due to their caloric value, which is similar to that of sucrose, but because of their physical properties, such as low crystallization tendency and moisture-binding capacity, which permitted the inclusion of higher concentrations of sugar-equivalent solids without compromising texture or palatability. Unlike sucrose, which can crystallize at high concentrations and sometimes produce gritty or brittle textures in certain formulations, corn syrups remain smooth and stable, making them ideal for dense confections, snack bars, syrups, and beverages.
Additionally, corn syrups are hygroscopic, meaning they draw and retain moisture. This moisture-binding property made it possible to produce soft, chewy, shelf-stable foods—a key feature of modern ultraprocessed snack items. Foods such as energy bars, soft cookies, and gummy candies rely on this combination of high caloric density and pleasant texture, which corn syrup facilitates. Sucrose lacks comparable moisture retention and can cause foods to dry out over time if not carefully formulated. Again, compare the texture of a homemade cake made with butter and sugar a week after baking to a sweet snack cake that may be palatable—or perhaps still tasty—even a year after it’s been produced. Corn syrup’s compatibility with fats and its role in extrusion processes also allowed the fusion of carbohydrates and lipids in products like frosted cereals, pastries, and snack cakes—many of which deliver high calories in compact, portable formats.
But it isn’t just Big Food itself doing all this. Just as Big Pharma has its hands in the government’s pocket, so does Big Food. And Uncle Sam is as much at fault as anyone else in the obesity and diabetes epidemic.
These functional advantages were reinforced by the economic incentives built into the U.S. food system. Corn-derived products are made artificially cheap through federal subsidies and market interventions such as sugar import quotas and price supports, which created strong incentives to substitute HFCS for sucrose. This cost advantage encouraged widespread substitution of HFCS for sucrose in sweetened beverages, condiments, and baked goods. By the mid-1980s, HFCS had surpassed sucrose as the primary sweetener in U.S. soft drinks. Its high solubility, clarity, and stability in cold liquids—with the addition of its artificially low cost thanks to indirect subsidies—made it the preferred sweetener for soda production, helping make sweetened beverages one of the most calorie-dense and widely consumed sources of sugar in the American diet. [My bold]
Processed foods increase the rate at which we eat them.
Refined processed carbohydrates in ultraprocessed foods are characterized by their soft, easy to chew nature that allows for food to be eaten quickly, swallowed effortlessly, and absorbed rapidly. In a controlled feeding study, researchers studied how fast people ate meals consisting of ultraprocessed versus unprocessed foods. The diets were matched for their calories, macronutrients, sugar, sodium, and fiber, but not their oral-sensory properties. The structure and texture of the foods in the ultraprocessed versus unprocessed test meals was different. Participants ate the ultraprocessed meals significantly faster.
Speed eating is no accident. The food industry designs food to go down in a whoosh. A patent application to produce corn chips that are as friction-free as potato chips makes this clear. The patent specifies the desired textural attributes: crispness, crunchiness, and lightness. The challenge in meeting those goals is that conventional corn chips and tortilla chips are “undesirably gritty.” The thicker cell walls of corn make these snack foods slower to break down as we chew, and they do not melt in our mouths. Like the potato chips and Goldfish crackers that were included among the ultraprocessed snacks in the NIH study, these corn chips would achieve a high degree of “mouthmelt.” They would disappear into the gut much faster than fresh fruit, raisins, or nuts, all snacks that actually require us to chew.
Light in the hand, the improved corn chip is crisp without being hard in the mouth, and crunchy but not gritty in the gut. Producing that structure begins with crushing the kernels into minute particles. In a separate step, starch is cooked in water and similarly pulverized, and the corn and starch are commingled and fed into extruders that break down the grain’s structure into “a highly gelatinized plasticized mass.” The resulting starch is a pale imitation of its molecular ancestor. Almost pre-chewed, it is quickly dissolved, swallowed, and absorbed in the upper GI tract, never reaching the colon. The gelatinous mass might have imparted “a distinct fresh roasted taste to corn chips and a toasted taste to wheat chips,” as the industry boasts, but satiety never sets in no matter how many chips are consumed. Rather, we consume chip after chip after chip.
Although all of the above and the rest of the petition make a great case for removing processed, refined carbs from the GRAS rating, what we don’t really have is long-term dietary studies showing harm. Or showing that people when presented with ultra-processed foods will consume vastly more calories than those who don’t.
We’ve discussed this in previous editions of The Arrow. As it stands now, there are only three randomized, controlled crossover trials looking at UPF and increased food consumption. One study by Keven Hall’s group shows that those subjects who consumed UPF ate ~500 calories more per day than those who ate minimally processed foods. But the study had people on the different diets for only two weeks with no wash out period in between. There has also been a Japanese study showing those who ate UPF consumed a bit over 800 calories per day more, but it was only a one-week study with two weeks of washout in between trials.
A recent study by Dicken et al from the UK had two groups following a UPF vs minimally processed diet for 8 weeks with a 4 week washout in between. There was a slight difference in weight loss between those following the minimally processed diet and those on the UPF diet, but not much to write home about. Those on the MPD lost about 4 pounds while those on the UPF arm lost not quite 2 pounds.
The problem with all these studies is that they are just too short. When I wrote about this a few weeks ago, I used going on a cruise as an example. When you get on the ship there is food everywhere, and you (at least I, can’t speak for others) eat like a hog. But once the novelty is over after a few days, you don’t eat nearly as much as you did the the first day or two.
We don’t know what would happen in a long-term study of, say, 6 months, or even a year. Would people adapt to the UPF diet and end up backing off the calories as time passed? Or would they—for all the reasons Dr. Kessler presented—eat vastly more and become obese? We just don’t know.
If I had to place a major bet on it, I would bet that those subjects in the UPF arm would gain weight. But that’s just a guess.
We know it happens in rats.
Dr. Kessler showed one such study. I’m sure there are many others.

The chow diet is in orange. The weight constantly goes up even on the chow diet because rodents continue to gain weight throughout their lives.
You can see what happened, though, when they added what they call “supermarket foods.” It’s not pretty. My bet is that it is driven by the increase in processed, refined carbs. In fact, it’s pretty obvious that it is. But would it work the same on humans? I suspect so, but we just don’t have the long-term studies we need to lock it in.
I know I quoted a lot from the Kessler petition, but it was just a fraction of the information there. I would encourage you to read it, because it is chock full of information.
My guess is that they will never take refined, processed foods off the GRAS list. But if they were ever going to do so, the next few years would be the time.
Are There Plastics In Canned Drinks?
I ran across this video this morning. It is pretty impressive and upsetting.
“Oh I avoid plastics, this is why I drink from a can”
You mean the plastic bag in your can?
— Brian Roemmele (@BrianRoemmele)
1:39 PM • Jul 18, 2025
Once I watched it, I began to look for substantiation one way or another. As it turns out, canned beverages do indeed have plastic sacks inside them. But, surprisingly, studies have shown that canned drinks shed fewer microplastics than do glass-bottled beverages. And the microplastic originate from the painted caps on the bottles. I haven’t had the chance to run to the store and grab a bottle of my favorite sparkling water, Mountain Valley Water, from Hot Springs, Arkansas, MD’s home town.
As I recall, they have a metal cap on them. But I’ve never really turned it over and looked at it from the bottom.
Watching that video gave me the creeps. And discovering that all aluminum cans have plastic liners creeped me out even more.
I will put some time and effort into looking deeper into this. And will let you know what I find out.
Odds and Ends
Why are some rabbits in Colorado growing horns on their heads? Are there really jackalopes? Surely Pfizer is working on a vax for this!
The Alaska sale: Why Russia sold it to the United States and how the deal is viewed 158 years later.
Did the Rapa Nui people us a technique called ‘parbbuckling’ to leverage the 12-ton hats onto their giant Easter Island Statues?
A new hue—olo—foreign to human sight? Scientists claim to have found color no one has seen before.
2.6 million-year-old stone tools reveal ancient human relatives were 'forward planning' 600,000 years earlier than thought.
Astronomers recently discovered radio waves emitted in space over 10 billion years ago.
It’s from their moms not their dads that young chimpanzees pick up their communication styles. (Probably young humans, too.)
MSNBC will soon be renamed as MS NOW, meaning "My Source for News, Opinion and the World." In other words, if you like the opinions MS NOW loves to report, that’s the station for you.
The rise of carnivore babies. About time!
The only diamond mine in North America is in Murfreesboro, AR (near where MD grew up and the fictional town that is the setting for her romance series Caddo Bend). At Crater of Diamonds state park, where you can search for your own diamonds and keep your finds. A woman just found her engagement diamond.
As individual as a fingerprint, they say ... or a snowflake. But in this gallery of close up actual photographs of them, snow crystals are far more beautiful, IMHO.
Making one 18th/19th Century featherbed required the feathers of 1,700 passenger pigeons (presumably fewer geese or ducks or chickens). And at $1 a pound, feathers were pricier than a gallon of whisky at the time of the Revolution.
Perhaps the most famous staircase nowadays would be Led Zeppelin's Stairway to Heaven...' But of the brick and mortar type, these 11 famous (and some quite outrageous) staircases would give that one a run for the money. Of the 11, MD and I have climbed but one. We’ve got our work cut out for us.
The roar of a lion can be heard from 5 miles away. Good thing, too, because it gives you time to beat feet. And a lion's roar isn't even the loudest sound a member of the animal kingdom makes!
Of the 10 Most Visited Museums in the world, MD and I have been to 6, most of them multiple times. And the other 4 are a world away!
Saturday night will be moonless, or more correctly display a 'black moon', which in itself isn't much to see. What it offers instead is a dark night for an unlighted glimpse of the galaxy.
What is it that makes the perfect chocolate? Follow the science.
The unusual offerings on the global McDonald's menu aren’t at all like the one on Main Street USA.
It's one thing to catch a falling star, but another when one lands in your pocket! The strange tale of an Alabama woman hit by a meteor.
DaVinci's flying machine created from 500 year old drawing. What a piece of work.
Video of the Week
The VOTW isn’t going to be a music video. It’s a hilarious skit about climate change.
Remember, climate change is predicted by modeling. And all models show what their designers want them to show. If you think about it, it’s pretty difficult to add everything that might affect the climate into a model. When and where do you put the volcanic eruptions or the giant earthquakes beneath the sea that blast billions of gallons of water into the atmosphere. It’s pretty difficult to get it right, so most people just guess based on their ideology. At least it’s good for a laugh.
Time for the poll, so you can grade my performance this week.
How did I do on this week's Arrow? |
That’s about it for this week. Keep in good cheer, and I’ll be back next Thursday.
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